(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-3-carboxylic acid
(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-3-carboxylic acid
CAS: 1217829-96-3
Molecular Formula: C16H20BrNO4
(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-3-carboxylic acid - Names and Identifiers
(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-3-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C16H20BrNO4 |
| Molar Mass | 370.24 |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD23105792 |
(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-3-carboxylic acid - Introduction
(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-3-carboxylic acid is an organic compound commonly known by the abbreviation Boc-methanesulfonyl-oxazole methyl ester. The following is a description of its nature, use, preparation and safety information:
Nature:
-Chemical formula: C18H24BrNO4S
-Molecular weight: 416.36g/mol
-Appearance: Colorless to pale yellow crystalline solid
-melting point: 81-83 ℃
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide
Use:
Boc-methanesulfonyl-oxazole methyl ester is a common protecting group, which is often used in the protection reaction in organic synthesis. It can be reacted with amine compounds to generate the corresponding Boc protected amine, in order to avoid the target product in the synthesis process is not affected by the unexpected reaction. It is widely used in drug synthesis, peptide synthesis and other organic chemical synthesis.
Preparation Method:
Boc-methanesulfonyl-oxazole methyl ester is usually prepared by Boc protection reaction. A common method is to react 1-(tert-oxypropoxy) methanesulfonic acid oxazole methyl ester with 4-bromoaniline, followed by a deprotection reaction to obtain the target product.
Safety Information:
- Boc-methanesulfonyl-oxazole methyl ester is not directly harmful to human health in its pure form.
-However, as an organic compound, it may cause irritation to the respiratory system, skin and eyes.
-When using or handling the compound, appropriate laboratory safety measures, such as wearing appropriate protective glasses, gloves and masks, and ensuring that the operation is carried out in a well-ventilated environment.
Nature:
-Chemical formula: C18H24BrNO4S
-Molecular weight: 416.36g/mol
-Appearance: Colorless to pale yellow crystalline solid
-melting point: 81-83 ℃
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide
Use:
Boc-methanesulfonyl-oxazole methyl ester is a common protecting group, which is often used in the protection reaction in organic synthesis. It can be reacted with amine compounds to generate the corresponding Boc protected amine, in order to avoid the target product in the synthesis process is not affected by the unexpected reaction. It is widely used in drug synthesis, peptide synthesis and other organic chemical synthesis.
Preparation Method:
Boc-methanesulfonyl-oxazole methyl ester is usually prepared by Boc protection reaction. A common method is to react 1-(tert-oxypropoxy) methanesulfonic acid oxazole methyl ester with 4-bromoaniline, followed by a deprotection reaction to obtain the target product.
Safety Information:
- Boc-methanesulfonyl-oxazole methyl ester is not directly harmful to human health in its pure form.
-However, as an organic compound, it may cause irritation to the respiratory system, skin and eyes.
-When using or handling the compound, appropriate laboratory safety measures, such as wearing appropriate protective glasses, gloves and masks, and ensuring that the operation is carried out in a well-ventilated environment.
Last Update：2024-04-09 20:45:29
Supplier List
View History